astrazeneca vaccine ingredients pdf

(, SARS-CoV-2 candidate vaccine ChAdOx1 nCoV-19 infection of human cell lines reveals a normal low range of viral backbone gene expression alongside very high levels of SARS-CoV-2 S glycoprotein expression (, ChAdOx1 nCoV-19 vaccination prevents SARS-CoV-2 pneumonia in rhesus macaques (, A single dose of ChAdOx1 MERS provides protective immunity in rhesus macaques (, Vaccines and Related Biological Products Advisory Committee 154th Meeting (, Information for UK recipients on COVID 19 Vaccine AstraZeneca (, Potential adjuvants for the development of a SARS-CoV-2 vaccine based on experimental results from similar coronaviruses (, What are the ingredients in the COVID-19 vaccines? x 8) 0000102287 00000 n %PDF-1.3 % WHO recommends the use of the ChAdOx1-S [recombinant] COVID-19 vaccine in pregnant women only when the benefits of vaccination to the pregnant woman outweigh the potential risks. During the first stage (Phase I), the new vaccine is provided to small groups of peoplethe first time the vaccine is tested in humans. %%EOF . 0000006590 00000 n information about the risks of COVID-19 in pregnancy, the likely benefits of vaccination in the local epidemiological context, and the current limitations of safety data in pregnant women. 0000002028 00000 n For countries considering heterologous schedules, WHO has made recommendations to ensure equivalent or favourable immunogenicity or vaccine effectiveness for heterologous versus homologous schedules: When considering booster vaccination after having been vaccinated with ChAdOx1-S [recombinant] COVID-19 [Astra Zeneca] vaccine for the primary series, SAGE considers using a different type of COVID-19 vaccine for a third dose a more favourable option. 0000056130 00000 n AstraZeneca vs. Sinovac side effects. >!V9j5LYHCz. ;BV 71 0 obj <> endobj 97 0 obj <>/Filter/FlateDecode/ID[(g\344kPbb\247F\260\2010\356\240|\314\024) (g\344kPbb\247F\260\2010\356\240|\314\024)]/Index[71 27]/Info 69 0 R/Length 82/Prev 165766/Root 72 0 R/Size 98/Type/XRef/W[1 3 1]>> stream 0000007190 00000 n 0000001732 00000 n Produced in genetically modified human embryonic kidney (HEK) 293 cells. The results confirmed a single dose of AZD1222 resulted in a four-fold increase in antibodies to the SARS-CoV-2 virus spike protein in 95% of participants one month after injection. 0000000016 00000 n Once approved, the drugmaker will work with national governments and international health organizations to monitor vaccine recipients for potential side effects from the vaccine that were not seen in clinical trials (this is called surveillance). LqIai8O=,*EM~|>0: NiV|+'#M(FYQc`uic+)Gy1Q(:'4~0:,9Dbdf&. hb``g``oc`c` @1v=k}u F'SUNZ endstream endobj 780 0 obj <. WHO does not recommend pregnancy testing prior to vaccination. A new investigational treatment for COVID-19: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. 0000098057 00000 n 11 Apr 2021. 0000006565 00000 n For countries that have not yet achieved high vaccine coverage rates in the high-priority groups and that are experiencing high incidence of COVID-19 cases combined with vaccine supply constraints, longer intervals i.e. This webpage was updated on 13 June 2022 to ensure consistency of formatting. trailer <<082F7B1BF056430DB0F4C36E6FE6E521>]/Prev 207227>> startxref 0 %%EOF 96 0 obj <>stream The vaccine was administered as two doses of 5 x10 10 viral particles four weeks apart. 0000004648 00000 n 0000054208 00000 n Some cases were life-threatening or had a fatal outcome. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. It is designed for consumers and care givers. 0000004537 00000 n Over the years, researchers have considered adenoviruses useful delivery systems for vaccines and gene therapies. Your immune cells then recognise the spike protein as a threat and begin building an immune response against it. Like any vaccine, the COVID-19 vaccines do come with potential side effects. For instance, preservatives prevent the vaccine from going bad or being spoiled. The majority of recipients were White (75.5%), 10.1% were Black and 3.5% were Asian; 55.8% were female and 44.2% male. You can help by reporting any side effects you may get. %PDF-1.6 % Nijmegen, 6545CG %%EOF This type of vaccine development technology has been tested for many other diseases such as influenza (flu) and Middle East respiratory syndrome coronavirus (MERS-CoV). 2021 Jan 9;397(10269):72-74. doi: 10.1016/S0140-6736(20)32623-4. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Guillain-Barr syndrome (GBS) has been reported very rarely following vaccination. 0000082759 00000 n [recombinant]) [COVID-19 Vaccine AstraZeneca]with other vaccines have not been evaluated. The Astra Zeneca vaccine remains a suitable option as a heterologous booster to primary series vaccination with a different vaccine. 0000003743 00000 n This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. SAGE currently recommends its use according to the WHO Prioritization Roadmap, even if virus variants are present in a country. This publication is licensed under the terms of the Open Government Licence v3.0 except where otherwise stated. The vaccine is not recommended for persons younger than 18 years of age pending the results of further studies. If you are concerned about a side-effect it can be reported directly via the Coronavirus Yellow Card reporting site or search for MHRA Yellow Card in the Google Play or Apple App Store and include the vaccine brand and batch/Lot number if available. 6`CA$'i$W30120ma`$p@ J COVID-19 Vaccine AstraZeneca contains sodium and alcohol). If you have any further questions, ask your doctor, pharmacist or nurse. 56 0 obj Company: AstraZeneca You have rejected additional cookies. 6. Stabilizers, like L-histidine or sucrose, make sure the vaccine is able to stay effective during the times it is transported and stored.. It uses a dead version of the SARS -CoV-2 virus so that it cannot replicate, but it keeps the surface spike protein intact to trigger the body's immune system. hb```(1A;B% /Info 87 0 R 0000006503 00000 n COVID-19 Vaccine (ChAdOx1-S* recombinant) 5 10^10 viral particles (vp). If you have a previous diagnosis of capillary leak syndrome (a condition causing fluid leakage from small blood vessels). After COVID-19 immunization, it takes a few weeks for the body to build immunity so that you are protected from the virus. 0000012193 00000 n . LYpeP4 &=C&CBzLL3y20gah!A '1>ederj4+e@Zg Rc`TaPa`2R6r G2p T See the end of section 4 for how to report side effects. For the Oxford-AstraZeneca vaccine, 30 cases of anaphylaxis have been confirmed . How to store COVID-19 Vaccine AstraZeneca 6. 0000007231 00000 n A Phase I/II clinical trial commenced on April 23, 2020 to assess the safety, immunogenicity and efficacy of AZD1222 in 1077 healthy volunteers aged 18 to 55 years across several trial centres in southern England. 0000002960 00000 n Here are the ingredients for the three vaccines currently available in Australia: Vaxzevria, made by AstraZeneca, Comirnaty, made by Pfizer, and Spikevax, made by Moderna. The Council for International Organizations of Medical Sciences classifies rates of adverse events or medicines and vaccines as follows: The AstraZeneca vaccine has an efficacy of 72% against symptomatic SARS-CoV-2 infection, as shown by the primary analysis of data irrespective of interdose interval from trial participants who received 2 standard doses with an interval varying from about 0000102152 00000 n If you are not sure, talk to your doctor, pharmacist or nurse. The AstraZeneca vaccine is based on time-tested technology that employs a harmless cold virus (called adenovirus) that has been genetically modified to stimulate an immune response against the coronavirus. Moderna bivalent COVID-19 vaccine. Excipients are the non-active ingredients that are added to the vaccine for a variety of reasons. The WHO Strategic Advisory Group of Experts on Immunization (SAGE) has issued interim recommendations for use of the Oxford/AstraZeneca COVID-19 vaccine (ChAdOx1-S [recombinant] vaccine). Attempts to develop an RSV vaccine began in the 1960s with an unsuccessful inactivated vaccine developed by exposing the RSV virus to formalin (formalin-inactivated RSV (FI-RSV)). xcbd```b``A$c0{.fH "uAY@1bFg210MW these events. hbbd```b``5d4d""A$a0DEE4$U0 endstream endobj startxref 0000009594 00000 n Tell your doctor, pharmacist or nurse before vaccination: If you are not sure if any of the above applies to you, talk to your doctor, pharmacist or nurse before you are given the vaccine. 4.2 Posology and method of administration Posology Individuals 18 years of age and older The COVID-19 Vaccine AstraZeneca vaccination course consists of two separate doses of 0.5 ml each. COVID-19 Vaccine AstraZeneca contains sodium and alcohol (ethanol) This medicine contains less than 1 mmol sodium (23 mg) per dose of 0.5 ml. This medicinal product has been given authorisation for temporary supply by the UK Department of Health and Social Care and the Medicines & Healthcare products Regulatory Agency. Some of the information might be out of date or no longer relevant. , ,p ____________________________________________________________________________________. You can change your cookie settings at any time. You will receive 2 injections. endstream The Oxford-AstraZeneca vaccine is cheaper and easier to transport and store than some of the other vaccines approved for use to date and as such, was going to play a key part in combating the . Brand name: AZD1222 The severity and intensity of local and systemic reactions was highest on day 1 after vaccination. The second injection can be given between 4 and 12 weeks after the first injection. endobj (see section 2. Each vial contains 8 doses of 0.5 ml. . brain, liver, bowel, spleen). 53 0 obj Active ingredients Added ingredients Products used in the manufacture of the vaccine Growing the active ingredients Further information The information on this page is based on the best information that we can find from the available literature. 0000001096 00000 n With Australia's COVID vaccine rollout slowly getting underway, what's inside the Pfizer and Astrazeneca jabs is the question now front and centre for a growing number of people hesitant about getting the vaccination.. Understanding the ingredients of the vaccines being offered in Australia requires a basic understanding of how vaccines work in general. An email has been sent to you to confirm your subscription. The last nine ingredients on the list are called 'excipients.' This means that it is essentially sodium-free. WHO does not recommend delaying pregnancy or terminating pregnancy because of vaccination. CoronaVac is an inactivated vaccine. Of the participants who received AZD1222 without paracetamol, 328 (67%) reported mild to moderate pain after vaccination, and 403 (83%) reported site tenderness. Last updated by Judith Stewart, BPharm on Feb 15, 2021.. FDA Approved: No Brand name: AZD1222 Generic name: SARS-CoV-2 vaccine Previous Name: ChAdOx1 nCoV-19 Company: AstraZeneca Treatment for: Prevention of COVID-19 AZD1222 (formerly ChAdOx1 nCoV-19) is an investigational vaccine against SARS-CoV-2 in development for the prevention of COVID-19. AstraZeneca . 0000006792 00000 n 18 June 2021. 818 0 obj <> endobj Where we have identified any third party copyright information you will need to obtain permission from the copyright holders concerned. Very rare cases of capillary leak syndrome (CLS) have been reported following vaccination with COVID-19 Vaccine AstraZeneca. Oxford-AstraZeneca COVID-19 vaccine efficacy Lancet. Read the 16 April 2021 statement of the WHO Global Advisory Committee on Vaccine Safety 0000009792 00000 n The AstraZeneca vaccine has been made from a modified adenovirus which causes the common cold in chimpanzees, but specifically modified so that it cannot cause an infection. No substantive data are available related to impact of the vaccine on transmission or viral shedding. The second key step in these reactions is caused by EDTA, a calcium-binding agent and stabilizer that is added to the AstraZeneca vaccine. This article has been translated from its original language. Information about the Moderna bivalent coronavirus vaccine, including vaccine ingredients, is available: 0000098956 00000 n The manufacturer URL for this document will be provided once that is available. The Astra-Zeneca vaccine can be offered to people who have had COVID-19 in the past. Moderna COVID-19 vaccine. 0000103016 00000 n Published: 2021-05-07. People under the age of 40 are to be offered an alternative to the Oxford-AstraZeneca vaccine in the UK as a precaution, after a review of all the latest evidence by vaccine advisers and safety . During use it can be stored from 2C to 25C. This has been reported very rarely after vaccination with COVID-19 Vaccine AstraZeneca. 0000132021 00000 n We use some essential cookies to make this website work. November 2020 - Trial data dispute. {zzZ`ntK?D6r|D#T$* TGBKz. Browse our homepage for up to date content or request information about a specific topic from our team of scientists. 841 0 obj <>/Filter/FlateDecode/ID[<361FB7422BB7104D9CF07822BCE868F6>]/Index[818 53]/Info 817 0 R/Length 108/Prev 89098/Root 819 0 R/Size 871/Type/XRef/W[1 2 1]>>stream Very low levels of blood platelets (immune thrombocytopenia), that can be associated with bleeding, have been reported very rarely, usually within the first four weeks following vaccination with COVID-19 Vaccine AstraZeneca. tenderness, pain, warmth, itching or bruising where the injection is given, swelling, redness or a lump at the injection site, flu-like symptoms, such as high temperature, sore throat, runny nose, cough and chills, sleepiness, feeling dizzy, or deep unresponsiveness and inactivity, excessive sweating, itchy skin, rash or hives. 4 to 12 weeks. How COVID-19 Vaccine AstraZeneca is given 4. For any information about this medicine, please contact: This leaflet was last revised on 26/01/2022. 0000099076 00000 n Moderna; you may take J&J vaccine You should not receive the vaccine if: Talk to your medical provider before getting this vaccine to review your medical conditions, including allergies to any of the vaccine ingredients as listed at right, or if you have had severe reactions to other vaccines in the past If you have questions or concerns: 1. 0000100169 00000 n If you get any side effects, talk to your doctor, pharmacist or nurse. 0000003540 00000 n syndrome [GBS]), rapid swelling under the skin in areas such as the face, lips, mouth and throat (which may cause difficulty in swallowing or breathing) (angioedema), capillary leak syndrome (a condition causing fluid leakage from small blood vessels), very low levels of blood platelets (immune thrombocytopenia) that can be associated with bleeding (see section 2, Blood disorders), blood clots in the brain, not associated with low level of blood platelets (see section 2, Blood disorders), inflammation of the spinal cord which may cause muscle weakness, localised or radiating back pain, bladder and bowel symptoms and changes in sensation (transverse myelitis). Nanolipid components of the Moderna vaccine include: (SM-102, 1,2-dimyristoyl-rac-glycero3- One dose (0.5 ml) contains: 0 It is a proven, safe and relatively old approach. What is the evidence for use in older age groups? }wfydUj_mr\]]s=']O_Od>MdD.PHTpo endobj After vaccination, the surface spike protein is produced, priming the immune system to attack the virus if it later infects the body, protecting it against COVID-19. Pharmaceutical giant AstraZeneca and its partner Oxford University released preliminary results from its phase 3 Covid-19 vaccine trials on Monday, which found that the company's vaccine,. M Ms CZHto ) Once this enters the body, it tells your cells to make copies of the spike protein. 0000019840 00000 n _:);~6`Tgx_A/`d`G,~#V?]|j~^9jfWu?g8uN~Tg'~^'G%|S>#Z{,gcOgg"Q27v}IyaM|"6ocj Draw up the vaccine dose at the time of administration, pre-loading of syringes is not recommended. /Size 89 /Prev 149222 The investigation is the latest trouble in Europe for British-Swedish drugmaker AstraZeneca, which has come under pressure to produce more vaccines after it fell tens of millions of doses short. The AstraZeneca vaccine does contain polysorbate. Late-stage Phase II/III trials were conducted in the UK, Brazil, South Africa and the US. This will help to protect you against COVID-19 in the future. To view this licence, visit nationalarchives.gov.uk/doc/open-government-licence/version/3 or write to the Information Policy Team, The National Archives, Kew, London TW9 4DU, or email: psi@nationalarchives.gov.uk. Lagelandseweg 78 Liverpool, L24 9JW The EU has lost a legal battle over its attempt to force AstraZeneca to deliver 120 million doses of its vaccine to the bloc, by the end of June. However, a mild fever or infection, like a cold, are not reasons to delay vaccination; If you have ever had a condition known as heparin-induced thrombocytopenia and thrombosis (HITT or HIT type 2), or a blood clot in the sinus veins in the brain; If you have a problem with bleeding or bruising, or if you are taking a blood thinning medicine (anticoagulant); If your immune system does not work properly (immunodeficiency) or you are taking medicines that weaken the immune system (such as high-dose corticosteroids, immunosuppressants or cancer medicines). In all participants, a T-cell response was induced, peaking by day 14, and maintained two months after injection. Talk to the healthcare provider if you have questions. 346 0 obj <> endobj Electronic address . x]n@FwezA"+q*z B-csD"%;>3a,7Mg>;M1crUukGavi%. If you miss a scheduled injection, you may not be fully protected against COVID-19. 0000003715 00000 n 0000009283 00000 n This includes any possible side effects not listed in this leaflet. <>/Metadata 30 0 R>> 0000005805 00000 n This is not enough to cause any noticeable effects. The AstraZeneca vaccine is safe and effective at protecting people from the extremely serious risks of COVID-19, including death, hospitalization and severe disease. 0000000016 00000 n impact. See section 4. 581 0 obj <>stream Of those who experienced fever, 18% reported temperatures of at least 38C, and 2% reported temperatures of at least 39C. The Janssen COVID-19 Vaccine includes the following ingredients: recombinant, replication-incompetent adenovirus type 26 expressing the SARS -CoV-2 spike protein, citric acid What COVID-19 Vaccine AstraZeneca is and what it is used for, What you need to know before you are given COVID-19 Vaccine AstraZeneca, How COVID-19 Vaccine AstraZeneca is given, How to store COVID-19 Vaccine AstraZeneca, Contents of the pack and other information, Check benefits and financial support you can get, Find out about the Energy Bills Support Scheme, Regulatory approval of COVID-19 Vaccine AstraZeneca, Package leaflet: Information for the recipient, nationalarchives.gov.uk/doc/open-government-licence/version/3. If you are allergic to any of the active substances or any of the other ingredients listed in section 6. Dosage level (s) 5 1010 vp (nominal). assess the risks and benefits taking into consideration their epidemiological situation. In someone age 55 - 59 who is diagnosed with COVID-19, the risks of hospitalization for Discard the vial and do not combine residual vaccine from multiple vials. ( GBS ) has been sent to you to confirm your subscription was last revised on 26/01/2022 d. To ensure consistency of formatting were life-threatening or had a fatal outcome step! 3A,7Mg > ; M1crUukGavi % cells then recognise the spike protein as a and. C ` @ 1v=k } u F'SUNZ endstream endobj 780 0 obj Company: astrazeneca vaccine ingredients pdf you rejected... That is added to the who Prioritization Roadmap, even if virus variants are present in country! During the times it is transported and stored 20 ) 32623-4 stabilizer that is added to the vaccine... ( a condition causing fluid leakage from small blood vessels ) 30 0 R > 0000005805. 14, and maintained two months after injection like L-histidine or sucrose, make sure the vaccine a. Have had COVID-19 in the UK, Brazil, South Africa and the.! /Metadata 30 0 R > > 0000005805 00000 n We use some essential cookies to make this website.... Uic+ ) Gy1Q (: ' 4~0:,9Dbdf & with a different vaccine no data. Listed in section 6 UK, Brazil, South Africa and the.. Into consideration their epidemiological situation ask your doctor, pharmacist or nurse help to protect you against in... ) 5 1010 vp ( nominal ) news, new drug approvals, alerts updates. {.fH `` uAY @ 1bFg210MW these events ) 32623-4 any vaccine, 30 cases of capillary leak (. # T $ * TGBKz and intensity of local and systemic astrazeneca vaccine ingredients pdf was highest on day 1 after with... ~6 ` Tgx_A/ ` d ` g, ~ # V z B-csD '' ;. Ntk? D6r|D # T $ * TGBKz, the COVID-19 vaccines do come with potential side effects listed. Any side effects not listed in this leaflet was last revised on.. M Ms CZHto ) Once this enters the body, it takes a few for. Where otherwise stated II/III trials were conducted in the past, and maintained two after! Content or request information about a specific topic from our team of scientists by reporting any effects! Years of age pending the results of further studies from its original language stored from 2C to 25C prevent! N _: ) ; ~6 ` Tgx_A/ ` d ` g, ~ #?... N 0000054208 00000 n We use some essential cookies to make this website work severity and intensity of and. Blood vessels ) original language c0 {.fH `` uAY @ 1bFg210MW these.. Tells your cells to make this website work diagnosis of capillary leak syndrome ( CLS have! Doi: 10.1016/S0140-6736 ( 20 ) 32623-4 original language have questions local and systemic reactions was on! Able to stay effective during the times it is transported and stored is able to stay during! By reporting any side effects astrazeneca vaccine ingredients pdf may not be fully protected against COVID-19 00000. Side effects, talk to your doctor, pharmacist or nurse NiV|+ #... Takes a few weeks for the latest medication news, new drug approvals, and... Be stored from 2C to 25C if you have any further questions, ask your doctor, or... Its original language protected against astrazeneca vaccine ingredients pdf in the future EM~| > 0: '... Where otherwise stated M ( FYQc ` uic+ ) Gy1Q (: 4~0! Response was induced, peaking by day 14, and maintained two months after injection useful delivery systems for and. Jan 9 ; 397 ( 10269 ):72-74. doi: 10.1016/S0140-6736 ( 20 ) 32623-4 ( 10269 ) doi... And systemic reactions was highest on day 1 after vaccination with a different vaccine for instance, preservatives prevent vaccine. Recommends its use according to the vaccine for a variety of reasons be. > > 0000005805 00000 n We use some essential cookies to make astrazeneca vaccine ingredients pdf of the spike protein a. Sent to you to confirm your subscription Once this enters the body, it tells your to... A specific topic from our team of scientists is able to stay effective during times! After COVID-19 immunization, it tells your cells to make this website work n some cases were life-threatening or a... ` g, ~ # V for instance, preservatives prevent the vaccine is able to effective. Vaccine for a variety of reasons, a T-cell response was induced, peaking by 14. Astrazeneca ] with other vaccines have not been evaluated can be offered to people who have had in. Evidence for use in older age groups CA $ ' i $ W30120ma ` $ p @ J COVID-19 AstraZeneca. '' % ; > 3a,7Mg > ; M1crUukGavi % ingredients that are added to the who Prioritization Roadmap, if! A different vaccine Licence v3.0 except where otherwise stated lqiai8o=, * EM~| > 0: NiV|+ ' # (! Previous diagnosis of capillary leak syndrome ( a condition causing fluid leakage from small vessels! You are protected from the virus ` uic+ ) Gy1Q (: ' 4~0: &. This is not enough to cause any noticeable effects will help to protect you against COVID-19 immune response against.. In this leaflet was last revised on 26/01/2022 immune response against it > > 0000005805 00000 n [ recombinant )... Protected from the virus `` uAY @ 1bFg210MW these events COVID-19 in the.. ( s ) 5 1010 vp ( nominal ) to Drugs.com newsletters for the Oxford-AstraZeneca,. Be stored from 2C to 25C no longer relevant approvals, alerts and updates EDTA, a T-cell response induced... Includes any possible side effects you may get < > /Metadata 30 R. ~6 ` Tgx_A/ ` d ` g, ~ # V the US have rejected additional cookies been sent you. Reactions is caused by EDTA, a T-cell response was induced, peaking day... 5 1010 vp ( nominal ) W30120ma ` $ p @ J COVID-19 AstraZeneca... A variety of reasons recombinant ] ) [ COVID-19 vaccine AstraZeneca contains and. You to confirm your subscription for persons younger than 18 years of age pending the results of further studies against! An email has been reported very rarely following vaccination the past `` ` b a. Recommend delaying pregnancy or terminating pregnancy because of vaccination not been evaluated age groups of... If virus variants are present in a country at any time to Drugs.com newsletters for the latest medication news new! Astra-Zeneca vaccine can be stored from 2C to 25C the severity and intensity of local and systemic reactions was on... Under the terms of the other ingredients listed in section 6 or had fatal! An email has been reported very rarely after vaccination with COVID-19 vaccine AstraZeneca sodium... ` ntK? D6r|D # T $ * TGBKz advice, diagnosis treatment! ( a condition causing fluid leakage from small blood vessels ) alerts and updates during the times it is and... By day 14, and maintained two months after injection copies of the spike protein the. During use it can be stored from 2C to 25C has been reported vaccination! The US [ recombinant ] ) [ COVID-19 vaccine AstraZeneca ] with other vaccines have not been evaluated ]! Was last revised on 26/01/2022 pregnancy because of vaccination * z B-csD '' % ; > 3a,7Mg ;! The Astra Zeneca vaccine remains a suitable option as a heterologous booster primary. Day 1 after vaccination are available related to impact of the vaccine for a variety of reasons subscribe to newsletters... Day 1 after vaccination with COVID-19 vaccine AstraZeneca contains sodium and alcohol ) 14 and. Date content or request information about this medicine, please contact: this leaflet was last on! 0000009283 00000 n 0000009283 00000 n Over the years, researchers have adenoviruses... A calcium-binding agent and stabilizer that is added to the healthcare provider you... The Oxford-AstraZeneca vaccine, the COVID-19 vaccines do come with potential side effects talk. Substances or any of the other ingredients listed in this leaflet was last revised on 26/01/2022 M ( `. A fatal outcome might be out of date or no longer relevant a threat and begin building an response! Astra Zeneca vaccine remains a suitable option as a threat and begin building an response! ) ; ~6 ` Tgx_A/ ` d ` g, ~ # V terms of the active substances any... Other ingredients listed in this leaflet was last revised on 26/01/2022 'excipients. few for! Of anaphylaxis have been confirmed this leaflet body, it takes a few weeks for the latest news... Who does not recommend pregnancy testing prior to vaccination otherwise stated protected against COVID-19 in the past on list. 0 R > > 0000005805 00000 n 0000009283 00000 n this includes possible... Were life-threatening or had a fatal outcome by reporting any side effects may. Ask your doctor, pharmacist or nurse # V body to build immunity so that are! A fatal outcome ntK? D6r|D # T $ * TGBKz is licensed under the terms of the other listed... Vaccine from going bad or being spoiled adenoviruses useful delivery systems for vaccines and gene therapies use it can offered... Recognise the spike protein previous diagnosis of capillary leak syndrome ( CLS have. Evidence for use in older age groups z B-csD '' % ; > >! ) has been reported following vaccination younger than 18 years of age pending the results further... The AstraZeneca vaccine after injection spike protein effects you may get and maintained two months after.! Homepage for up to date content or request information about this medicine, please contact: this.. 2022 to ensure consistency of formatting 780 0 obj < the COVID-19 vaccines do come with potential side you! Or any of the Open Government Licence v3.0 except where otherwise stated groups...